With rapid developments in nanomedicine, magnetic nanoparticles (MNPs) have appeared as an encouraging theranostics tool in biomedical applications involving drug delivery, diagnostic imaging, and novel therapeutics. Substantial pre-clinical and clinical studies have demonstrated their targeted delivery, controlled drug release, functionalization, and image-guided capabilities. MNPs may accumulate at the targeted site through active or passive targeting to enhance the therapeutic efficacy by functionalization with targeting ligands and drugs.107,108 Among numerous described methodologies, static-magnetic- field-based- magnetically guided brain delivery systems have been proven to be harmless and noninvasive. Successful delivery of drug-loaded nanoformulations (NFs) to the mouse brain has previously been achieved by applying this method. This technique appears to be appropriate for delivering magnetic, drug-loaded NFs into the CNS to offer maximum efficiency in tackling specific neurological diseases. It is expected that the delivered therapeutics will have very modest or no adverse side-effects on the patient in terms of motor coordination, motor function, and toxicity.109 To extract the SARS-CoV-2 viral RNA for detection by real-time polymerase chain reaction (RT-PCR), magnetic nanoparticles were used in research. By imparting magnetic nature to nanoparticles through encapsulation of superparamagnetic iron oxide nanoparticles (SPIONs), which helped to isolate the nanoparticle-bound virus pathogen using an external magnet. The virus extracted maintained its infectivity and could be identified using several diagnostic assays for viruses.110